A trial vaccine has succeeded in removing aging cells from the body of mice, and the authors believe it could be a step towards a similar vaccine in humans, according to a new study.
In a study published in the journal “Natural agingThe vaccine modified some of the symptoms of age-related diseases in mice, helping to extend their lifespan.
“The research data are strong and, in theory, may work in humans at the same time,” says Paul Robbins, associate director and professor of biochemistry at the University of Minnesota’s Institute of Aging and Metabolic Biology.
Move site “Direct scienceRegarding Robins not involved in the study, the big question is whether the vaccine is safe for humans, he said, adding that researchers should conduct further studies in animals and other safe experiments on some humans.
Aging occurs as a result of cells stopping to grow due to damage or stress, but they do not die, but instead secrete inflammatory compounds that accumulate as we age, thus damaging healthy cells.
After being vaccinated, the immune system learns to find and destroy cells that have stopped multiplying, the researchers said.
In the experiment, the researchers focused on cells in the arteries, nerves and capillaries, and analyzed the proteins that appear in large numbers in these cells, helping to target them through vaccination.
Researchers have found that a protein accumulates in tissues with age and causes many diseases, including cancerous growths.
They focused on making the vaccine on this protein, and after vaccinating the rats, their immune systems began to attack and destroy it, and the vaccinated rats lived relatively longer than their unvaccinated counterparts.
Doru Minamno, senior author of the study and professor at Jundento University Medical School and director of cardiology at Jundento University Hospital in Tokyo, told the site that the group plans to develop additional vaccines that target other aging cells in the body.
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